MDOI Convergence Chronicles 110.0668/CON.2026.00640
110.0668/CON.2026.00640
Article

Zero Dollar Copay Pharmacy Benefit Decreases Healthcare Expenditures Among Members With Type 2 Diabetes of Blue Cross Blue Shield of Louisiana

Tiange Tang, MPH, Charles Stoecker, PhD, Debra Winberg, PhD, Miao Liu, MS, Elizabeth Nauman, PhD, Mingyan Cong, PhD, Eboni Price-Haywood, MD, MPH, Brice Labruzzo Mohundro, PharmD, Alessandra N. Bazzano, PhD, Lizheng Shi, PhD, on behalf of the Louisiana Experiment Assessing Diabetes Outcomes (LEAD)-ZDC Working Group 2025 Convergence Chronicles

Abstract

Objectives Blue Cross Blue Shield of Louisiana implemented the Zero Dollar Copay (ZDC) program on July 1, 2020. This study aims to evaluate whether the ZDC program can reduce total healthcare expenditures. Methods Blue Cross Blue Shield of Louisiana’s medical and pharmacy claims from January 2019 to December 2021 was used in this study, and the index date was July 1, 2020. We identified 7603 continuously enrolled members with type 2 diabetes, including 3045 ZDC-eligible members as the ZDC group and 4558 Administrative Service Only group members as the control group. The primary outcome measure was monthly total healthcare expenditure, which included monthly medical and pharmacy spending. ZDC program’s effectiveness was evaluated by a 2-way fixed-effect difference-in-difference regression weighted by odds of propensity scores. The study population was further classified into 3 subgroups based on their baseline use of ZDC-eligible antidiabetic medications: pre-ZDC users, pre-ZDC nonusers, and complex users. Results The ZDC pharmacy benefit was associated with a significant reduction in total healthcare spending of $−121.76 per member per month (PMPM) (P = .002) and medical spending of $−131.50 PMPM (P < .001). For complex users, the ZDC program was associated with reductions of $283.44 PMPM (P = .006) in total healthcare spending and $385.45 PMPM (P < .001) in medical spending, whereas pharmacy spending significantly increased by $102.01 PMPM (P = .022). No significant results were observed for pre-ZDC users and pre-ZDC nonusers.

Identifier Metadata

Identifier 110.0668/CON.2026.00640
Canonical mdoi:110.0668/CON.2026.00640
Resolver URL https://mdoi.org/110.0668/CON.2026.00640
Resource URL Open resource
Document URL Open document
Content Type Article
Authors Tiange Tang, MPH, Charles Stoecker, PhD, Debra Winberg, PhD, Miao Liu, MS, Elizabeth Nauman, PhD, Mingyan Cong, PhD, Eboni Price-Haywood, MD, MPH, Brice Labruzzo Mohundro, PharmD, Alessandra N. Bazzano, PhD, Lizheng Shi, PhD, on behalf of the Louisiana Experiment Assessing Diabetes Outcomes (LEAD)-ZDC Working Group
Year 2025
Depositor Convergence Chronicles Organisation
Prefix 110.0668
Registered July 17, 2026
Updated July 17, 2026
Status Active
Visibility Public

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