MDOI Convergence Chronicles 110.0602/CON.2026.00576
110.0602/CON.2026.00576
Article

The Argument-Based Approach to Validity Applied to Clinical Outcome Assessments: Some History and Notable Features

Kevin P. Weinfurt, PhD 2025 Convergence Chronicles

Abstract

Developing and evaluating clinical outcome assessments (COAs) requires a framework for understanding validity. The validity framework reflected in the most recent draft guidance from the US Food and Drug Administration is the argument-based approach. In this approach, a researcher should state how they would like to interpret or use scores from some measure, identify key assumptions that need to be true for the proposed interpretation/use to be justified, and evaluate evidence for or against those key assumptions. If the collection of assumptions, known as the rationale, has convincing evidence, then a decision is made that the proposed interpretation or use of scores is valid. In this article, I briefly review how this approach to validity that has been developed within educational and psychological testing has recently made its way into COAs. I then discuss several notable features of the argument-based approach that have implications for how COAs are developed and evaluated.

Identifier Metadata

Identifier 110.0602/CON.2026.00576
Canonical mdoi:110.0602/CON.2026.00576
Resolver URL https://mdoi.org/110.0602/CON.2026.00576
Resource URL Open resource
Document URL Open document
Content Type Article
Authors Kevin P. Weinfurt, PhD
Year 2025
Depositor Convergence Chronicles Organisation
Prefix 110.0602
Registered July 13, 2026
Updated July 13, 2026
Status Active
Visibility Public

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