MDOI Convergence Chronicles 110.0548/CON.2026.00522
110.0548/CON.2026.00522
Article

Changes in Out-of-Pocket Drug Expenditures Among Medicare Beneficiaries With Dementia Under the Inflation Reduction Act: A Simulation Study

Yingying Zhu, PhD, Natalia Olchanski, PhD, Karen M. Freund, MD, MPH, Joshua T. Cohen, PhD, Peter J. Neumann, ScD, Pei-Jung Lin, PhD 2025 Convergence Chronicles

Abstract

Objectives We investigated how the Inflation Reduction Act (IRA) Medicare Part D benefit redesign may reduce out-of-pocket (OOP) drug expenditures for Medicare beneficiaries with dementia. Methods Using data from the Health and Retirement Study (HRS) linked with Medicare claims, we simulated post-redesign OOP drug spending by applying the 2025 prescription drug cost-sharing rules to each beneficiary’s pre-redesign Part D medication utilization for 2016, adjusting for inflation. Our study population comprised HRS respondents aged 65 and older in 2016, enrolled in Medicare fee for service, with at least one Part D drug claim in 2016, and diagnosed with dementia between 2000 and 2016 (n = 1677). We compared pre-redesign and post-redesign annual OOP drug expenditures stratified by: (1) low-income subsidy (LIS) eligibility status; (2) household income among non-LIS beneficiaries; (3) comorbidity count, and 4) cognitive impairment severity. Results After the redesign, we project average annual OOP drug expenditures among LIS beneficiaries with dementia to decrease from $56 to $25—representing a $31, or 55%, reduction. In contrast, among non-LIS beneficiaries, average OOP drug expenditures is projected to decrease from $772 to $576, a $196, or 25% reduction. We project the reduction in OOP drug expenditures to be greater among beneficiaries with 6 to 8 comorbidities (45%) than among beneficiaries with fewer comorbidities (21%-26%). Conclusions The Inflation Reduction Act Medicare Part D benefit redesign will reduce OOP drug spending for beneficiaries with dementia, resulting in potentially marked savings not only for low-income beneficiaries and beneficiaries with a high comorbidity burden but also for higher-income beneficiaries.

Identifier Metadata

Identifier 110.0548/CON.2026.00522
Canonical mdoi:110.0548/CON.2026.00522
Resolver URL https://mdoi.org/110.0548/CON.2026.00522
Resource URL Open resource
Document URL Open document
Content Type Article
Authors Yingying Zhu, PhD, Natalia Olchanski, PhD, Karen M. Freund, MD, MPH, Joshua T. Cohen, PhD, Peter J. Neumann, ScD, Pei-Jung Lin, PhD
Year 2025
Depositor Convergence Chronicles Organisation
Prefix 110.0548
Registered July 9, 2026
Updated July 9, 2026
Status Active
Visibility Public

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