Changes in Out-of-Pocket Drug Expenditures Among Medicare Beneficiaries With Dementia Under the Inflation Reduction Act: A Simulation Study
Abstract
Objectives We investigated how the Inflation Reduction Act (IRA) Medicare Part D benefit redesign may reduce out-of-pocket (OOP) drug expenditures for Medicare beneficiaries with dementia. Methods Using data from the Health and Retirement Study (HRS) linked with Medicare claims, we simulated post-redesign OOP drug spending by applying the 2025 prescription drug cost-sharing rules to each beneficiary’s pre-redesign Part D medication utilization for 2016, adjusting for inflation. Our study population comprised HRS respondents aged 65 and older in 2016, enrolled in Medicare fee for service, with at least one Part D drug claim in 2016, and diagnosed with dementia between 2000 and 2016 (n = 1677). We compared pre-redesign and post-redesign annual OOP drug expenditures stratified by: (1) low-income subsidy (LIS) eligibility status; (2) household income among non-LIS beneficiaries; (3) comorbidity count, and 4) cognitive impairment severity. Results After the redesign, we project average annual OOP drug expenditures among LIS beneficiaries with dementia to decrease from $56 to $25—representing a $31, or 55%, reduction. In contrast, among non-LIS beneficiaries, average OOP drug expenditures is projected to decrease from $772 to $576, a $196, or 25% reduction. We project the reduction in OOP drug expenditures to be greater among beneficiaries with 6 to 8 comorbidities (45%) than among beneficiaries with fewer comorbidities (21%-26%). Conclusions The Inflation Reduction Act Medicare Part D benefit redesign will reduce OOP drug spending for beneficiaries with dementia, resulting in potentially marked savings not only for low-income beneficiaries and beneficiaries with a high comorbidity burden but also for higher-income beneficiaries.
Identifier Metadata
| Identifier | 110.0548/CON.2026.00522 |
| Canonical | mdoi:110.0548/CON.2026.00522 |
| Resolver URL | https://mdoi.org/110.0548/CON.2026.00522 |
| Resource URL | Open resource |
| Document URL | Open document |
| Content Type | Article |
| Authors | Yingying Zhu, PhD, Natalia Olchanski, PhD, Karen M. Freund, MD, MPH, Joshua T. Cohen, PhD, Peter J. Neumann, ScD, Pei-Jung Lin, PhD |
| Year | 2025 |
| Depositor | Convergence Chronicles Organisation |
| Prefix | 110.0548 |
| Registered | July 9, 2026 |
| Updated | July 9, 2026 |
| Status | Active |
| Visibility | Public |
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