MDOI Convergence Chronicles 110.0545/CON.2026.00519
110.0545/CON.2026.00519
Article

Cost-Effectiveness of a Digitally Supported Care Management Program for Caregivers of People With Dementia

Michelle Pfaff, MSc, Wolfgang Hoffmann, MD, MPH, Melanie Boekholt, MA, Olga Biernetzky, PhD, Iris Blotenberg, PhD, Dilshad Afrin, MSc, Moritz Platen, PhD, Stefan Teipel, MD, Jochen René Thyrian, PhD, Ingo Kilimann, MD, Bernhard Michalowsky, PhD 2025 Convergence Chronicles

Abstract

Objectives To examine the cost-effectiveness of a digitally supported care management system (CMS) for caregivers of people with dementia (PwD) compared with usual care. Methods The analysis was based on 192 caregivers (n = 96 CMS, n = 96 usual care) of PwD in a cluster-randomized controlled trial testing a digitally supported CMS, aiming to identify and address caregivers’ unmet needs and develop and implement an individualized support and care plan over 6 months. Incremental costs from the public-payer and societal perspectives, quality-adjusted life years (QALY), and the incremental cost-effectiveness ratio 6 months after baseline were calculated using multivariate regression models. We assessed the probability of cost-effectiveness using a range of willingness-to-pay thresholds. Results Caregivers in the intervention group gained QALYs (+0.004 [95% CI −0.003 to 0.012], P value = .225) and had lower costs from the public payer (−378€ [1926-1168], P value = .630), but higher costs from the societal perspective (+1324 [−3634 to 6284], P value = .599). The intervention dominated usual care from the payer perspective, whereas the incremental cost-effectiveness ratio was €331 000/QALY from a societal perspective. The probability of cost-effectiveness was 72% and 79% from the public payer and 33% and 35% from a societal perspective at the willingness-to-pay thresholds threshold of €40 000 and €80 000/QALY gained. Conclusions CMS was likely cost-effective from the payer but not from a societal perspective, underlining the importance of informal care. The gain in QALY was marginal and could be due to the short observation period. Focusing on both the caregiver and the PwD, rather than assessing the PwD needs through the caregiver, could improve the cost-effectiveness results.

Identifier Metadata

Identifier 110.0545/CON.2026.00519
Canonical mdoi:110.0545/CON.2026.00519
Resolver URL https://mdoi.org/110.0545/CON.2026.00519
Resource URL Open resource
Document URL Open document
Content Type Article
Authors Michelle Pfaff, MSc, Wolfgang Hoffmann, MD, MPH, Melanie Boekholt, MA, Olga Biernetzky, PhD, Iris Blotenberg, PhD, Dilshad Afrin, MSc, Moritz Platen, PhD, Stefan Teipel, MD, Jochen René Thyrian, PhD, Ingo Kilimann, MD, Bernhard Michalowsky, PhD
Year 2025
Depositor Convergence Chronicles Organisation
Prefix 110.0545
Registered July 9, 2026
Updated July 9, 2026
Status Active
Visibility Public

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